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PET/MR Evaluation of Regression Grading After Neoadjuvant Therapy for Rectal Cancer - Trial NCT06318234

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NCT06318234
Recruiting
diagnostic test
Trial Details
ClinicalTrials.gov โ€ข NCT06318234
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PET/MR Evaluation of Regression Grading After Neoadjuvant Therapy for Rectal Cancer
Research Focused on Developing and Assessing a Non-intrusive Diagnostic Approach for Grading Tumor Regression Post-neoadjuvant Treatment in Rectal Cancer, Utilizing 18F-FAPI in Conjunction With FDG PET/MR Imaging.

Study Focus

Rectal Cancer

18F-FAPI๏ผŒ18F-FDG

Observational

diagnostic test

Sponsor & Location

Xiao Chen

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Chongqing, China

Timeline & Enrollment

N/A

Jan 01, 2024

Dec 31, 2025

32 participants

Primary Outcome

Evaluation efficacy of tumor regression level

Summary

This project aims to evaluate the role of 18F-FAPI combined with 18F-FDG PET/MRI imaging in
 quantitatively and accurately evaluating the grading of rectal cancer after SCRT neoadjuvant
 therapy in patients with advanced rectal cancer as the research object, with postoperative
 histopathological analysis as the reference index, and to assess the ability of patients to
 achieve pCR. A diagnostic model and evaluation system will also be constructed.

ICD-10 Classifications

Malignant neoplasm of rectum
Carcinoma in situ: Rectum
Benign neoplasm: Rectum
Secondary malignant neoplasm of large intestine and rectum
Carcinoma in situ: Rectosigmoid junction

Data Source

ClinicalTrials.gov

NCT06318234

Non-Device Trial