The Effect of Aerosol Formed From Tobacco Heating Systems on the Microbiome of Supragingival Dental Biofilm - Trial NCT06314100
Access comprehensive clinical trial information for NCT06314100 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Rijeka and is currently Completed. The study focuses on Dental Caries. Target enrollment is 60 participants.
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Study Focus
Sponsor & Location
University of Rijeka
Timeline & Enrollment
N/A
Oct 01, 2021
Oct 25, 2023
Primary Outcome
diversity of bacterial species,abundance of bacterial species,caries risk
Summary
Dental caries is a multifactorial disease primarily caused by supragingival dental biofilm.
 Its progression is influenced by many environmental factors, which include smoking. Tobacco
 heating systems (THS) are a novel tobacco product whose effect on the microbiome of the
 supragingival dental biofilm has not yet been investigated.
 
 The aim of the proposed research is to determine and compare the composition of the
 microbiomes of the supragingival dental biofilm of THS smokers, cigarette smokers, and
 nonsmokers using the Next Generation Sequencing method and to assess and compare the risk of
 new caries lesion formation between the test groups using the Cariogram method.
 
 The results of this research will provide insight into changes in the microbiome of the
 supragingival dental biofilm resulting from exposure to aerosols from tobacco combustion and
 tobacco heating.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06314100
Device Trial