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A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004) - Trial NCT06307431

Access comprehensive clinical trial information for NCT06307431 through Pure Global AI's free database. This Phase 2 trial is sponsored by Merck Sharp & Dohme LLC and is currently Recruiting. The study focuses on Renal Cell Carcinoma. Target enrollment is 272 participants.

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NCT06307431
Phase 2
Recruiting
biological
Trial Details
ClinicalTrials.gov โ€ข NCT06307431
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A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004)
A Phase 2, Randomized, Double-blind, Clinical Study of V940 (mRNA-4157) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in the Adjuvant Treatment of Participants With Renal Cell Carcinoma

Study Focus

Renal Cell Carcinoma

V940

Interventional

biological

Sponsor & Location

Merck Sharp & Dohme LLC

New Haven,New York,Macquarie University,Quรฉbec,Santiago,Santiago,Santiago,Viรฑa del Mar,Taipei, Australia,Canada,Chile,Taiwan,United States of America

Timeline & Enrollment

Phase 2

Apr 10, 2024

Jun 08, 2032

272 participants

Primary Outcome

Disease-Free Survival (DFS)

Summary

The primary objective of the study is to compare V940 plus pembrolizumab to placebo plus
 pembrolizumab with respect to disease-free survival (DFS) as assessed by the investigator.
 The primary hypothesis is that V940 plus pembrolizumab is superior to placebo plus
 pembrolizumab with respect to DFS.

ICD-10 Classifications

Malignant neoplasm of kidney, except renal pelvis
Malignant neoplasm of renal pelvis
Secondary malignant neoplasm of kidney and renal pelvis
Benign neoplasm: Kidney
Benign neoplasm: Renal pelvis

Data Source

ClinicalTrials.gov

NCT06307431

Non-Device Trial