Head Down Tilt 15° to Increase Collateral Flow in Acute Ischemic Stroke - Trial NCT06297863
Access comprehensive clinical trial information for NCT06297863 through Pure Global AI's free database. This Phase 2 trial is sponsored by University of Milano Bicocca and is currently Not yet recruiting. The study focuses on Acute Ischemic Stroke. Target enrollment is 118 participants.
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Study Focus
Sponsor & Location
University of Milano Bicocca
Timeline & Enrollment
Phase 2
Oct 01, 2024
Dec 31, 2026
Primary Outcome
Good collateral status
Summary
The DOWN-SUITE study is multicenter, randomised, controlled, open-label clinical trial with
 blinded outcome assessment comparing collateral status in patients with acute ischemic stroke
 treated with an in-hospital application of head down tilt -10° to -15° (HDT15) versus usual
 positioning (0° to +30°) before endovascular mechanical thrombectomy.
 
 This study will involve adult patients who are eligible for mechanical thrombectomy and who
 have acute ischemic stroke due to left or right middle cerebral artery occlusion (M1
 segment).
 
 The investigators hypothesise that HDT15, applied in acute ischemic stroke patients with a
 large vessel occlusion, will improve collateral circulation, prolong the survival of the
 ischemic penumbra and improve the clinical benefit from mechanical thrombectomy compared with
 standard of care (usual positioning 0° to +30°).
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06297863
Non-Device Trial