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A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21) - Trial NCT06295432

Access comprehensive clinical trial information for NCT06295432 through Pure Global AI's free database. This Phase 2 trial is sponsored by Dizal Pharmaceuticals and is currently Recruiting. The study focuses on Non-small Cell Lung Cancer. Target enrollment is 90 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06295432
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06295432
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A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)
A Phase II, Multicenter Study to Assess the Safety, Tolerability and Anti-tumor Efficacy of DZD9008 in Combination With AZD4205 in Standard Treatment Failed Non-Small Cell Lung Cancer (NSCLC) Patients With EGFR Mutations

Study Focus

DZD9008+AZD4205

Interventional

drug

Sponsor & Location

Dizal Pharmaceuticals

Guangzhou, China

Timeline & Enrollment

Phase 2

Jun 01, 2023

Jun 01, 2025

90 participants

Primary Outcome

Part A: incidence of DLT , โ‰ฅgrade 3 TEAEs and SAEs; Part B: incidence of โ‰ฅgrade 3 TEAEs as assessed by CTCAE, incidence of SAEs.

Summary

DZD9008 in combination with AZD4205 for the treatment of patients with advanced NSCLC with
 EGFR mutations who have progressed after standard treatment. The purpose of this study is to
 assess the safety and efficacy of this combination therapy.

ICD-10 Classifications

Secondary malignant neoplasm of lung
Malignant neoplasm: Lower lobe, bronchus or lung
Malignant neoplasm: Middle lobe, bronchus or lung
Malignant neoplasm: Bronchus or lung, unspecified
Malignant neoplasm of bronchus and lung

Data Source

ClinicalTrials.gov

NCT06295432

Non-Device Trial