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Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate - Trial NCT06282848

Access comprehensive clinical trial information for NCT06282848 through Pure Global AI's free database. This phase not specified trial is sponsored by The Hong Kong Polytechnic University and is currently Recruiting. The study focuses on Myopia. Target enrollment is 80 participants.

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NCT06282848
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Trial Details
ClinicalTrials.gov โ€ข NCT06282848
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Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate
Pharmacological (0.05% Atropine) and Non-pharmacological (Defocused Incorporated Multiple Segments Lens) Treatment Effects on the Children With Different Predicted Myopia Progression Rate Measured by Modified Multifocal Electroretinogram

Study Focus

Myopia

Atropine 0.05%

Interventional

drug

Sponsor & Location

The Hong Kong Polytechnic University

Hong Kong, China

Timeline & Enrollment

N/A

Jan 01, 2024

Dec 01, 2026

80 participants

Primary Outcome

Subjective refraction,Axial length

Summary

The goal of this clinical trial is to compare pharmacological and non-pharmacological
 treatment effects on the children with different predicted myopia progression rate measured
 by modified multifocal electroretinogram. The main questions it aims to answer are:
 
 - the effectiveness of using 0.05% atropine and prescribing DIMS lens for myopia control
 in children with different myopia progression rates
 
 - the contribution of L/M cones in juvenile myopia progression and changes of retinal
 activities under atropine and DIMS treatment.
 
 Participants will have baseline and follow-up eye examinations and given either
 pharmacological treatment with 0.05% atropine or non-pharmacological treatment with DIMS lens
 for myopia control.
 
 Researchers will compare the changes of refractive errors and axial length after different
 types of interventions and investigate the relations between the parameters of mfERG
 responses and the thicknesses of retinal layers and choroid.

ICD-10 Classifications

Myopia
Degenerative myopia
Amblyopia ex anopsia
Ocular myiasis
Myiasis

Data Source

ClinicalTrials.gov

NCT06282848

Non-Device Trial