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TYK2 Inhibition in Paradoxical Psoriasis - Trial NCT06281106

Access comprehensive clinical trial information for NCT06281106 through Pure Global AI's free database. This Phase 2/3 trial is sponsored by Prof Curdin Conrad and is currently Not yet recruiting. The study focuses on Psoriasis. Target enrollment is 26 participants.

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NCT06281106
Phase 2/3
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06281106
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TYK2 Inhibition in Paradoxical Psoriasis
Tyrosine Kinase 2 (TYK2) Inhibition in Paradoxical Psoriasis A Randomized, Double-blind, Placebo-controlled Multi-center Study Evaluating the Effect of Deucravacitinib on Severity of Psoriasis in Patients With Paradoxical Psoriasis

Study Focus

Psoriasis

Deucravacitinib

Interventional

drug

Sponsor & Location

Prof Curdin Conrad

Centre Hospitalier Universitaire Vaudois

Lausanne, Switzerland

Timeline & Enrollment

Phase 2/3

Apr 01, 2024

Aug 01, 2025

26 participants

Primary Outcome

Paradoxical Psoriasis Investigator Global Assessment

Summary

Paradoxical psoriasis is a side effect of a biological treatment (anti-tumor necrosis factor
 agent, short called anti-TNF) that is used to treat diseases of the skin, the intestine or
 the joints. If paradoxical psoriasis occurs, the anti-TNF-treatment often needs to be stopped
 and so far, no specific treatment for paradoxical psoriasis exists.
 
 This research project aims to study whether the efficacy of the drug 'Deucravacitinib' 6mg, a
 tablet taken by mouth once a day is superior compared to taking a placebo in treating
 paradoxical psoriasis.

ICD-10 Classifications

Psoriasis
Other psoriasis
Psoriasis, unspecified
Arthropathic psoriasis
Psoriasis vulgaris

Data Source

ClinicalTrials.gov

NCT06281106

Non-Device Trial