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Efficacy of Cadonilimab in Non-squamous Non-small Cell Lung Cancer Patients Resistant to EGFR-TKI - Trial NCT06277674

Access comprehensive clinical trial information for NCT06277674 through Pure Global AI's free database. This Phase 2 trial is sponsored by Guangzhou University of Traditional Chinese Medicine and is currently Recruiting. The study focuses on Non-small Cell Lung Cancer. Target enrollment is 20 participants.

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NCT06277674
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06277674
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Efficacy of Cadonilimab in Non-squamous Non-small Cell Lung Cancer Patients Resistant to EGFR-TKI
A Phase II Clinical Trial Evaluating the Efficacy of Cadonilimab in Combination With Pemetrexed and Anlotinib for Treatment of Elderly Patients With T790M-negative Advanced Non-squamous Non-small Cell Lung Cancer Following Resistance to EGFR-TKI.

Study Focus

Cadonilimab plus Pemetrexed and Anlotinib

Interventional

drug

Sponsor & Location

Guangzhou University of Traditional Chinese Medicine

Guangzhou, China

Timeline & Enrollment

Phase 2

Nov 02, 2023

Jun 01, 2025

20 participants

Primary Outcome

ORR(Objective response rate)

Summary

This study was designed to evaluate the efficacy and safety of cadonilimab (anti PD-1 and
 CTLA-4 bispecific antibody) in combination with pemetrexed and anlotinib for treatment of
 elderly patients with T790M-negative advanced non-squamous non-small cell lung cancer
 following resistance to EGFR-TKI.

ICD-10 Classifications

Secondary malignant neoplasm of lung
Malignant neoplasm: Lower lobe, bronchus or lung
Malignant neoplasm: Middle lobe, bronchus or lung
Malignant neoplasm: Bronchus or lung, unspecified
Malignant neoplasm of bronchus and lung

Data Source

ClinicalTrials.gov

NCT06277674

Non-Device Trial