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Polymorphism of ApoE in Alzheimer's Disease: Genetic Study in Castile and Leon (Spain) - Trial NCT06275243

Access comprehensive clinical trial information for NCT06275243 through Pure Global AI's free database. This phase not specified trial is sponsored by Universidad de León and is currently Recruitment Completed. The study focuses on Alzheimer Disease. Target enrollment is 511 participants.

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NCT06275243
Recruitment Completed
diagnostic test
Trial Details
ClinicalTrials.govNCT06275243
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Polymorphism of ApoE in Alzheimer's Disease: Genetic Study in Castile and Leon (Spain)
Alzheimer's Disease as a Sociosanitary Priority: ApoE Gene Polymorphism

Study Focus

Alzheimer Disease

Kit Buccal swab collection & stabilization de Canvax®

Interventional

diagnostic test

Sponsor & Location

Universidad de León

León, Spain

Timeline & Enrollment

N/A

Jul 06, 2022

Mar 22, 2024

511 participants

Primary Outcome

Distribution of ApoE variants in the Alzheimer's disease population diagnosed in Castile and Leon.

Summary

The general objective of this randomized and longitudinal clinical study was to estimate the
 frequencies of ApoE variants both in the user population of the Messengers of Peace
 Residences and the Associations of Relatives of Alzheimer's Patients in Castile y Leon,
 since, due to its geographical location at the crossroads, it has received multiple genetic
 contributions from both northern Europe, the Mediterranean area and northern Africa.
 
 The main questions it aims to answer are:
 
 - What are the allelic frequencies of ApoE variants in the population of individuals with
 Alzheimer's disease in Castile and Leon?
 
 - Is there a correlation between the ApoE4 variant and the lipid profile in the blood of
 individuals with Alzheimer's disease in this region?

ICD-10 Classifications

Alzheimer disease
Alzheimer disease, unspecified
Other Alzheimer disease
Dementia in Alzheimer disease
Dementia in Alzheimer disease, unspecified

Data Source

ClinicalTrials.gov

NCT06275243

Non-Device Trial