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Neoadjuvant Toripalimab for Clinically Stage II-IIIB Resectable Non-small Cell Lung Cancer With EGFR Mutation and PD-L1 Positive Expression - Trial NCT06269211

Access comprehensive clinical trial information for NCT06269211 through Pure Global AI's free database. This Phase 2 trial is sponsored by Ruijin Hospital and is currently Not yet recruiting. The study focuses on Carcinoma, Non-Small-Cell Lung. Target enrollment is 29 participants.

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NCT06269211
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06269211
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Neoadjuvant Toripalimab for Clinically Stage II-IIIB Resectable Non-small Cell Lung Cancer With EGFR Mutation and PD-L1 Positive Expression
Neoadjuvant Toripalimab for Clinically Stage II-IIIB Resectable Non-small Cell Lung Cancer With EGFR Mutation and PD-L1 Positive Expression: a Prospective, Open-label, Multicenter, Single-arm Phase II Clinical Study

Study Focus

Toripalimab

Interventional

drug

Sponsor & Location

Ruijin Hospital

Guangzhou,Shanghai, China

Timeline & Enrollment

Phase 2

Mar 30, 2024

Jan 31, 2030

29 participants

Primary Outcome

Major Pathological Response (MPR)

Summary

The study is a prospective, open label, multicenter, single arm Phase II clinical trial,
 aiming to explore the use of neoadjuvant Toripalimab for clinically stage II-IIIB NSCLC
 patients with EGFR mutations and PD-L1 positive expression, providing a novel perspective for
 further improving the prognosis of NSCLC patients. This study will provide valuable
 information for further clinical trials of neoadjuvant Toripalimab and other immune
 checkpoint inhibitors in NSCLC patients with EGFR mutations and PD-L1 positive expression.

ICD-10 Classifications

Carcinoma in situ: Bronchus and lung
Secondary malignant neoplasm of lung
Malignant neoplasm: Lower lobe, bronchus or lung
Malignant neoplasm: Bronchus or lung, unspecified
Malignant neoplasm of bronchus and lung

Data Source

ClinicalTrials.gov

NCT06269211

Non-Device Trial