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Anti-PD1 Monoclonal Antibody Combined With Nimotuzumab and Capecitabine in Patients With First-line Platinum-resistant Recurrent/Metastatic Nasopharyngeal Carcinoma - Trial NCT06259721

Access comprehensive clinical trial information for NCT06259721 through Pure Global AI's free database. This Phase 2 trial is sponsored by Jiangxi Provincial Cancer Hospital and is currently Recruiting. The study focuses on Nasopharyngeal Carcinoma. Target enrollment is 22 participants.

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NCT06259721
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06259721
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Anti-PD1 Monoclonal Antibody Combined With Nimotuzumab and Capecitabine in Patients With First-line Platinum-resistant Recurrent/Metastatic Nasopharyngeal Carcinoma
Efficacy and Safety of Anti-PD1 Monoclonal Antibody Combined With Nimotuzumab and Capecitabine in Patients With First-line Platinum-resistant Recurrent/Metastatic Nasopharyngeal Carcinoma: A Single-arm, Open-label, Multi-center Phase II Clinical Trial

Study Focus

Nasopharyngeal Carcinoma

Anti-PD1 antibody, nimotuzumab and capecitabine

Interventional

drug

Sponsor & Location

Jiangxi Provincial Cancer Hospital

Nanchang, China

Timeline & Enrollment

Phase 2

Feb 10, 2024

Aug 09, 2026

22 participants

Primary Outcome

Objective response rate

Summary

The purpose of this study is to explore the efficacy and safety of a combination regimen of
 Anti-PD1 monoclonal antibody, nimotuzumab, and capecitabin in treating recurrent or
 metastatic nasopharyngeal carcinoma patients who have failed first-line platinum-based
 chemotherapy.

ICD-10 Classifications

Malignant neoplasm of nasopharynx
Malignant neoplasm: Nasopharynx, unspecified
Malignant neoplasm: Overlapping lesion of nasopharynx
Benign neoplasm: Nasopharynx
Malignant neoplasm: Posterior wall of nasopharynx

Data Source

ClinicalTrials.gov

NCT06259721

Non-Device Trial