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A Study of Concurrent Chemoradiotherapy Followed by Cadonilimab(AK104) for Newly Diagnosed Local Advanced Cervical Cancer - Trial NCT06251388

Access comprehensive clinical trial information for NCT06251388 through Pure Global AI's free database. This Phase 2 trial is sponsored by West China Second University Hospital and is currently Recruiting. The study focuses on Cervical Cancer. Target enrollment is 50 participants.

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NCT06251388
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.govNCT06251388
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A Study of Concurrent Chemoradiotherapy Followed by Cadonilimab(AK104) for Newly Diagnosed Local Advanced Cervical Cancer
A Prospective, Single Arm, Multicenter, Phase II Study to Evaluate the Efficacy and Safety of Concurrent Chemoradiotherapy Followed by Cadonilimab(AK104) for Newly Diagnosed Local Advanced Cervical Cancer

Study Focus

Cervical Cancer

AK104

Interventional

drug

Sponsor & Location

West China Second University Hospital

Chengdu, China

Timeline & Enrollment

Phase 2

Feb 20, 2024

Oct 01, 2026

50 participants

Primary Outcome

Progression-free survival

Summary

This study will evaluate the efficacy and safety of concurrent
 chemoradiotherapy(CCRT)followed by cadonilimab(AK104) in high risk local advanced cervical
 cancer.
 
 Participants received CCRT,efficacy evaluation of CCRT was no disease progression who
 maintained with AK104(10.0 mg/kg,Q3W)until drug exposure over 1 years or disease progression
 or intolerable toxicity.

ICD-10 Classifications

Severe cervical dysplasia, not elsewhere classified
Mild cervical dysplasia
Moderate cervical dysplasia
Carcinoma in situ: Cervix, unspecified
Cervical root disorders, not elsewhere classified

Data Source

ClinicalTrials.gov

NCT06251388

Non-Device Trial