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Intradermal Ipilimumab and Nivolumab in High Risk Stage II Melanoma - Trial NCT06240143

Access comprehensive clinical trial information for NCT06240143 through Pure Global AI's free database. This Phase 1/2 trial is sponsored by The Netherlands Cancer Institute and is currently Not yet recruiting. The study focuses on Melanoma. Target enrollment is 80 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06240143
Phase 1/2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06240143
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Intradermal Ipilimumab and Nivolumab in High Risk Stage II Melanoma
Multicenter Phase 1b/2 Trial Testing Neoadjuvant Intradermal Ipilimumab and Nivolumab in High Risk Stage II Melanoma - MARIANE

Study Focus

Melanoma

Ipilimumab

Interventional

drug

Sponsor & Location

The Netherlands Cancer Institute

Amsterdam,Amsterdam,Groningen,Leiden,Rotterdam,Utrecht, Netherlands

Timeline & Enrollment

Phase 1/2

Feb 01, 2024

May 01, 2026

80 participants

Primary Outcome

Feasibility,Effectivity

Summary

This open label, single country trial will test if local injection of low-dose ipilimumab and
 nivolumab, is safe and reduces the sentinel node positivity in high-risk stage II melanoma
 patients.

ICD-10 Classifications

Malignant melanoma of skin
Melanoma in situ, unspecified
Melanoma in situ
Melanoma and other malignant neoplasms of skin
Malignant neoplasm: Malignant melanoma of skin, unspecified

Data Source

ClinicalTrials.gov

NCT06240143

Non-Device Trial