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Reduced-dose Radiotherapy for Stage III Nasopharyngeal Carcinoma Based on the Treatment Response - Trial NCT06239727

Access comprehensive clinical trial information for NCT06239727 through Pure Global AI's free database. This Phase 3 trial is sponsored by Sun Yat-sen University and is currently Not yet recruiting. The study focuses on Nasopharyngeal Carcinoma. Target enrollment is 593 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06239727
Phase 3
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06239727
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Reduced-dose Radiotherapy for Stage III Nasopharyngeal Carcinoma Based on the Treatment Response
Reduced-dose Radiotherapy for Stage III Nasopharyngeal Carcinoma Based on the Treatment Response: an Open Label, Non-Inferiority, Multicenter, Randomized Phase 3 Trial

Study Focus

Nasopharyngeal Carcinoma

PD-1 blocking antibody

Interventional

drug

Sponsor & Location

Sun Yat-sen University

Guangzhou,Zhongshan,Nanning,Guiyang,Wuhan,Wuhan,Changsha,Changsha, China

Timeline & Enrollment

Phase 3

Feb 20, 2024

Feb 20, 2030

593 participants

Primary Outcome

Locoregional failure-free survival (LRFFS)

Summary

This is an Open Label, Non-Inferiority, Multicenter, Randomized Phase 3 Trial aimed to
 investigate the impact of reduced-dose radiotherapy in combination with chemotherapy and
 immunotherapy on patients' prognosis and complication compared with conventional-dose
 radiotherapy in combination with chemotherapy and immunotherapy for treatment-sensitive stage
 III NPC patients screened out according to the treatment response.

ICD-10 Classifications

Malignant neoplasm of nasopharynx
Malignant neoplasm: Nasopharynx, unspecified
Malignant neoplasm: Overlapping lesion of nasopharynx
Benign neoplasm: Nasopharynx
Malignant neoplasm: Posterior wall of nasopharynx

Data Source

ClinicalTrials.gov

NCT06239727

Non-Device Trial