Energetics and Glutamate in Schizophrenia - Trial NCT06236048
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Study Focus
Sponsor & Location
King's College London
Timeline & Enrollment
N/A
Mar 01, 2024
Dec 01, 2028
Primary Outcome
Brain glucose utilisation,Glutamate - anterior cingulate cortex,Lactate - visual cortex,Cerebral blood flow,Cortical network activity
Summary
The goal of this case-control study is to compare brain glutamate, glucose utilisation,
 lactate production and brain activity in healthy volunteers and people with a diagnosis of
 schizophrenia.
 
 It investigates the following main questions:
 
 Whether, compared to healthy volunteers, participants with schizophrenia show:
 
 1. reduction in brain glucose utilisation
 
 2. increased brain lactate
 
 3. greater variability in brain glutamate
 
 Participants will be asked to have a screening visit, a MRI brain scan and a PET-MRI brain
 scan.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06236048
Non-Device Trial