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A Study of LY3537982 in Chinese Participants With Advanced Solid Tumors - Trial NCT06235983

Access comprehensive clinical trial information for NCT06235983 through Pure Global AI's free database. This Phase 1 trial is sponsored by Eli Lilly and Company and is currently Not yet recruiting. The study focuses on Advanced Solid Tumors. Target enrollment is 12 participants.

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NCT06235983
Phase 1
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06235983
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A Study of LY3537982 in Chinese Participants With Advanced Solid Tumors
An Open-label, Single-arm, Multicenter, Phase 1 Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Antitumor Activity of LY3537982 in Chinese Patients With KRAS G12C-Mutant Advanced Solid Tumors

Study Focus

Advanced Solid Tumors

LY3537982

Interventional

drug

Sponsor & Location

Eli Lilly and Company

Changsha,Changchun,Shanghai,Hangzhou,Hangzhou, China

Timeline & Enrollment

Phase 1

Feb 29, 2024

Apr 30, 2027

12 participants

Primary Outcome

Pharmacokinetics (PK): Maximum Observed Plasma Concentration (Cmax) of LY3537982,PK: Area Under the Plasma Concentration Versus Time Curve (AUC) of LY3537982

Summary

This is an open-label, single-arm, multicenter, Phase 1 study of LY3537982 as monotherapy in
 Chinese participants with KRAS G12C-mutant advanced solid tumors. The main purpose of this
 study is to determine how much of LY3537982 gets into the bloodstream and how long it takes
 the body to eliminate it in Chinese participants. The safety, tolerability and preliminary
 efficacy of LY3537982 will also be evaluated. Approximately 12 patients will be enrolled in
 this study.

ICD-10 Classifications

Malignant neoplasm: Prepuce
Carcinoma in situ, unspecified
Malignant neoplasm: Connective and soft tissue, unspecified
Malignant neoplasm: Parametrium
Malignant neoplasm: Orbit

Data Source

ClinicalTrials.gov

NCT06235983

Non-Device Trial