The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans - Trial NCT06218381
Access comprehensive clinical trial information for NCT06218381 through Pure Global AI's free database. This phase not specified trial is sponsored by Children's Hospital Los Angeles and is currently Recruiting. The study focuses on Post Traumatic Stress Disorder. Target enrollment is 80 participants.
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Study Focus
Sponsor & Location
Children's Hospital Los Angeles
Timeline & Enrollment
N/A
Mar 22, 2024
Jan 01, 2026
Primary Outcome
Mean Activation of Frontostriatal and Prefrontal Brain Regions to combat stimuli in PTSD
Summary
The goal of this clinical trial is to develop a new behavioral treatment for U.S. combat
 veterans with post-traumatic stress disorder (PTSD), very brief exposure to combat-related
 stimuli. The main questions it aims to answer are:
 
 1. How does Very Brief Exposure (combat images and control everyday images) and Visible
 Exposure to combat stimuli affect brain activity and subjective fear ratings?
 
 2. To what extent are participants aware of the stimuli presented and tolerating the
 exposures?
 
 All participants will view both very brief exposure and visible exposure to combat stimuli in
 the functional magnetic brain imaging (fMRI) scan. They will provide ratings of fear,
 awareness, and tolerability. Researchers will compare U.S. combat veterans with PTSD and
 healthy controls to confirm differences in brain region activation and ratings.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06218381
Non-Device Trial