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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer - Trial NCT06205485

Access comprehensive clinical trial information for NCT06205485 through Pure Global AI's free database. This Phase 3 trial is sponsored by Canadian Cancer Trials Group and is currently Not yet recruiting. The study focuses on Rectal Cancer. Target enrollment is 250 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06205485
Phase 3
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06205485
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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer
A Phase 3 Randomized Trial Of Neoadjuvant Chemotherapy, Excision And Observation Versus Chemoradiotherapy For Early Rectal Cancer

Study Focus

Rectal Cancer

Leucovorin

Interventional

drug

Sponsor & Location

Canadian Cancer Trials Group

Timeline & Enrollment

Phase 3

Mar 30, 2024

Jun 30, 2030

250 participants

Primary Outcome

Clinical response rate upon re-staging,Quality of Life defined using the LARS score

Summary

This study is being done to answer the following questions: Is the chance of rectal cancer
 responding the same if chemotherapy alone is given before limited surgery compared to
 chemotherapy and radiation therapy given together before limited surgery? If radiation
 therapy is not given, is quality of life better?

ICD-10 Classifications

Malignant neoplasm of rectum
Carcinoma in situ: Rectum
Benign neoplasm: Rectum
Secondary malignant neoplasm of large intestine and rectum
Carcinoma in situ: Rectosigmoid junction

Data Source

ClinicalTrials.gov

NCT06205485

Non-Device Trial