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TMS for Inhibition Enhancement in Schizophrenia - Trial NCT06155682

Access comprehensive clinical trial information for NCT06155682 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Maryland, Baltimore and is currently Not yet recruiting. The study focuses on Schizophrenia. Target enrollment is 34 participants.

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Trial Details
ClinicalTrials.gov โ€ข NCT06155682
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TMS for Inhibition Enhancement in Schizophrenia
Cognitive and Neural Correlates of TMS Motor Intracortical Inhibition in Schizophrenia

Study Focus

Schizophrenia

repetitive transcranial magnetic stimulation

Interventional

device

Sponsor & Location

University of Maryland, Baltimore

Timeline & Enrollment

N/A

Mar 01, 2025

Dec 01, 2028

34 participants

Primary Outcome

The change in the short interval intracortical inhibition (SICI) score

Summary

This study purpose is to perform a pilot mechanistic trial repetitive transcranial magnetic
 stimulation (rTMS) clinical trial in 34 people with schizophrenia (Sz). The trial will
 evaluate whether inhibitory 1 Hertz (Hz) rTMS targeting motor cortex can increase brain
 inhibition reflected in a decrease in the short-interval intracortical inhibition (SICI)
 score from pre-to-post-treatment. We will also collect preliminary data on the effect of rTMS
 on the resting functional connectivity of the motor cortex and other brain regions and the
 relationship of change in SICI to change in cognitive performance

ICD-10 Classifications

Schizophrenia
Simple schizophrenia
Schizophrenia, unspecified
Other schizophrenia
Paranoid schizophrenia

Data Source

ClinicalTrials.gov

NCT06155682

Device Trial