Profiling of Circulating Immune Cells to Uncover Response Signatures to Anti-PD1 Immunotherapy in Melanoma Patients - Trial NCT06154668
Access comprehensive clinical trial information for NCT06154668 through Pure Global AI's free database. This phase not specified trial is sponsored by University Hospital, Grenoble and is currently Not yet recruiting. The study focuses on Melanoma. Target enrollment is 707 participants.
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Study Focus
Observational
Sponsor & Location
University Hospital, Grenoble
Timeline & Enrollment
N/A
Dec 01, 2023
Dec 01, 2031
Primary Outcome
Identification of biomarkers of response to anti6PD1 according to the type of patient before the start of treatment
Summary
Despite being standard of care, there are still many medical requirements related to immune
 checkpoint blocker based therapies such as identify patients susceptible to respond with the
 less adverse events, evaluate the clinical benefit of adjuvant treatment /risk of relapse and
 design new strategies for non-responder patients.
 
 Thus, this project aims at understanding the impact of anti-PD1 on the immune system through
 investigation of the phenotypic, functional, metabolic and transcriptomic profiles of
 circulating DC subsets and effectors in response to anti-PD1 therapy in melanoma patients.
 
 The primary objective of the study is to identify the biomarkers of response to anti-PD1
 according to the type of patient before the start of the treatment.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06154668
Non-Device Trial