A COMPARISON OF TRANSDERMAL DICLOFENAC AND ORAL COMBINATION OF PARACETAMOL AND IBUPROFEN IN POSTOPERATIVE PAIN MANAGEMENT FOLLOWING SURGICAL EXTRACTION OF MANDIBULAR THIRD MOLAR- A RANDOMISD CONTROLLED TRIALS. - Trial NCT06146491
Access comprehensive clinical trial information for NCT06146491 through Pure Global AI's free database. This Phase 4 trial is sponsored by B.P. Koirala Institute of Health Sciences and is currently Recruiting. The study focuses on Pain, Postoperative. Target enrollment is 108 participants.
This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.
Study Focus
Sponsor & Location
B.P. Koirala Institute of Health Sciences
Timeline & Enrollment
Phase 4
Aug 10, 2023
Jan 15, 2024
Primary Outcome
To compare the analgesic effectiveness of diclofenac trans dermal patch (200mg) and oral combination of paracetamol (500mg) and ibuprofen (400mg) following surgical removal of mandibular third molar.
Summary
This is comparative interventional study, will be conducted in patient indicated for surgical
 extraction of mandibular third molar at the Department of Oral and Maxillofacial surgery,
 College of Dental Surgery, BPKIHS, Nepal. Verbal and written will be taken . Participants
 meeting inclusion criteria will be included in the study and will be divided in to two
 groups, group A (Oral combination of paracetamol-500mg and ibuprofen -400mg) and group B (
 Transdermal diclofenac patch-200mg) using computer generated randamization. Extraction will
 be carried out using standard protocol. Aformention drugs will given to participants
 accordingly for management of post operative pain.Tramadol will be given to each patient as
 rescue analgesics and allowed to have if pain score exceeds 7.post operative instruction will
 be given carefully. Rescue phone number will be provided in case of emergency. Telephonic
 interview will be performed at 12, 24 and 72 hours post operatively and pain score using
 numeric rating scale will be recorded.Any adverse effects of drugs will be recorded. The data
 collected will be entered in Microsoft excel sheet. It will then be transferred into SPSS
 (Statistical Package for Social Sciences) for statistical analysis.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06146491
Non-Device Trial