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A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With Head and Neck Cancer - Trial NCT06145412

Access comprehensive clinical trial information for NCT06145412 through Pure Global AI's free database. This Phase 2 trial is sponsored by Memorial Sloan Kettering Cancer Center and is currently Recruiting. The study focuses on Head and Neck Cancer. Target enrollment is 54 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06145412
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov • NCT06145412
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A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With Head and Neck Cancer
A Phase II Trial of Xevinapant in Combination With Post-Operative Cisplatin and Radiotherapy for High Risk Head and Neck Cancer

Study Focus

Head and Neck Cancer

Xevinapan

Interventional

drug

Sponsor & Location

Memorial Sloan Kettering Cancer Center

Basking Ridge,Middletown,Montvale,Commack,Harrison,New York,Uniondale, United States of America

Timeline & Enrollment

Phase 2

Nov 16, 2023

Nov 01, 2026

54 participants

Primary Outcome

Progression Free Survival

Summary

The purpose of this study is to test whether treatment with Xevinapant added to standard
 chemoradiation after surgery is an effective treatment for people with high-risk head and
 neck cancers.

ICD-10 Classifications

Malignant neoplasm of other and ill-defined sites: Head, face and neck
Malignant neoplasm: Skin of scalp and neck
Malignant neoplasm: Connective and soft tissue of head, face and neck
Carcinoma in situ: Skin of scalp and neck
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck

Data Source

ClinicalTrials.gov

NCT06145412

Non-Device Trial