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Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma - Trial NCT06129955

Access comprehensive clinical trial information for NCT06129955 through Pure Global AI's free database. This Phase 2 trial is sponsored by Sun Yat-sen University and is currently Not yet recruiting. The study focuses on Renal Cell Carcinoma. Target enrollment is 47 participants.

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NCT06129955
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06129955
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Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma
A Phase II Clinical Study on the Efficacy and Safety of Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma With Indications for Partial Nephrectomy But High Surgical Risk: A Single Arm Approach

Study Focus

Renal Cell Carcinoma

Pucotenlimab Combined With Lenvatinib

Interventional

drug

Sponsor & Location

Sun Yat-sen University

Guangzhou, China

Timeline & Enrollment

Phase 2

Nov 11, 2023

Dec 31, 2025

47 participants

Primary Outcome

ORR

Summary

Through the neoadjuvant treatment with a combination of Pucotenlimab and Lenvatinib, it
 eventually enables the successful and safe implementation of partial nephrectomy in patients
 with localized renal cancer, who have indications for nephron-sparing surgery but face
 significant difficulty in kidney preservation (T1b with an endophytic component โ‰ฅ75% or T2).

ICD-10 Classifications

Malignant neoplasm of kidney, except renal pelvis
Malignant neoplasm of renal pelvis
Secondary malignant neoplasm of kidney and renal pelvis
Benign neoplasm: Kidney
Benign neoplasm: Renal pelvis

Data Source

ClinicalTrials.gov

NCT06129955

Non-Device Trial