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The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC - Trial NCT06109558

Access comprehensive clinical trial information for NCT06109558 through Pure Global AI's free database. This phase not specified trial is sponsored by Hunan Province Tumor Hospital and is currently Not yet recruiting. The study focuses on Non Small Cell Lung Cancer. Target enrollment is 20 participants.

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NCT06109558
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Trial Details
ClinicalTrials.gov โ€ข NCT06109558
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The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC
A Prospective Clinical Research of Efficacy and Safety of LMV-12(HE003) Combined With Osimertini in the Treatment of Advanced Non-small Cell Lung Cancer That Has Previously Failed EGFR Inhibitor Therapy

Study Focus

LMV-12(HE003) and Osimertinib

Observational

drug

Sponsor & Location

Hunan Province Tumor Hospital

Changsha, China

Timeline & Enrollment

N/A

Nov 01, 2023

Nov 30, 2024

20 participants

Primary Outcome

ORR,PFS,DOR,DCR,OS

Summary

This is an open-label, single-arm, dose-escalation, multicenter phase I clinical trial. The
 primary endpoint of this study is to evaluated the safety, tolerability, pharmacokinetic
 profile and preliminary efficacy of HE003 in combination with osimertinib in patients with
 advanced solid tumors who have failed previous standard therapy.

ICD-10 Classifications

Secondary malignant neoplasm of lung
Malignant neoplasm: Lower lobe, bronchus or lung
Malignant neoplasm: Middle lobe, bronchus or lung
Malignant neoplasm: Bronchus or lung, unspecified
Malignant neoplasm of bronchus and lung

Data Source

ClinicalTrials.gov

NCT06109558

Non-Device Trial