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Periodontal Regeneration With Hyaluronic Acid or Enamel Matrix Derivatives - Trial NCT06105112

Access comprehensive clinical trial information for NCT06105112 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Turin, Italy and is currently Recruiting. The study focuses on Periodontitis. Target enrollment is 60 participants.

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Trial Details
ClinicalTrials.gov โ€ข NCT06105112
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Periodontal Regeneration With Hyaluronic Acid or Enamel Matrix Derivatives
Minimally Invasive Periodontal Regeneration With a Combination Approach Using Either Hyaluronic Acid or Enamel Matrix Derivatives: a 24-month Multicenter Randomized Controlled Clinical Trial

Study Focus

Periodontitis

Hyaluronic acid

Interventional

device

Sponsor & Location

University of Turin, Italy

Turin, Italy

Timeline & Enrollment

N/A

Oct 01, 2023

Oct 01, 2026

60 participants

Primary Outcome

Clinical attachment level change

Summary

To date, the quest for ideal biological inductors for periodontal regeneration is still
 ongoing, especially when facing non-containing defect anatomies. The primary aim of this
 study is to evaluate the clinical and radiographic performance of a bone graft combined with
 either enamel matrix derivatives or hyaluronic acid for periodontal regeneration of
 non-containing intrabony defects in terms of clinical attachment gain (primary outcome) and
 other secondary outcomes (probing pocket depth reduction, radiographic bone fill). Moreover,
 this study aims to compare early wound healing and patient-reported outcome measures.

ICD-10 Classifications

Chronic periodontitis
Periodontosis
Acute periodontitis
Chronic apical periodontitis
Periodontal disease, unspecified

Data Source

ClinicalTrials.gov

NCT06105112

Device Trial