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A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer - Trial NCT06099769

Access comprehensive clinical trial information for NCT06099769 through Pure Global AI's free database. This Phase 2 trial is sponsored by Memorial Sloan Kettering Cancer Center and is currently Recruiting. The study focuses on Metastatic Breast Cancer. Target enrollment is 201 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06099769
Phase 2
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06099769
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A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer
A RANDOMIZED, PHASE II STUDY OF ENZALUTAMIDE, ENZALUTAMIDE WITH MIFEPRISTONE, and TREATMENT OF PHYSICIAN'S CHOICE IN PATIENTS WITH AR+ METASTATIC TRIPLE-NEGATIVE OR ER-LOW BREAST CANCER

Study Focus

Metastatic Breast Cancer

Enzalutamide

Interventional

drug

Sponsor & Location

Memorial Sloan Kettering Cancer Center

Birmingham,San Francisco,Chicago,Boston,New York,Chapel Hill, United States of America

Timeline & Enrollment

Phase 2

Oct 18, 2023

Oct 01, 2027

201 participants

Primary Outcome

progression-free survival (PFS)

Summary

The researchers are doing this study to find out if the study drug, enzalutamide, alone or
 combined with the study drug, mifepristone, is effective in treating advanced or metastatic
 androgen receptor-positive (AR+) triple negative breast cancer (TNBC) or estrogen
 receptor-low breast cancer (ER-low BC), and whether these study treatments work as well as
 standard chemotherapy with carboplatin, paclitaxel, capecitabine, or eribulin.

ICD-10 Classifications

Malignant neoplasm of breast
Malignant neoplasm of breast
Malignant neoplasm: Breast, unspecified
Malignant neoplasm: Central portion of breast
Malignant neoplasm: Overlapping lesion of breast

Data Source

ClinicalTrials.gov

NCT06099769

Non-Device Trial