Interleukin 20 and Periodontal Tisuue Destruction - Trial NCT06091800
Access comprehensive clinical trial information for NCT06091800 through Pure Global AI's free database. This phase not specified trial is sponsored by Recep Tayyip Erdogan University and is currently Completed. The study focuses on Periodontitis. Target enrollment is 60 participants.
This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.
Study Focus
Sponsor & Location
Recep Tayyip Erdogan University
Timeline & Enrollment
N/A
Jun 06, 2022
Jun 06, 2023
Primary Outcome
concentration of biochemical findings in gingival crevicular fluid (GCF),concentration of biochemical findings in serum
Summary
Periodontitis is an inflammatory disease that causes destruction of periodontal tissues.
 IL-20, on the other hand, is known as a potent angiogenic, chemotactic, and pro-inflammatory
 cytokine associated with various chronic inflammatory disorders. IL-20 has a significant role
 in the regulation of osteoclastogenesis and osteoblastogenesis. The aim of this study was to
 evaluate the effect of IL-20 on periodontal destruction.
 
 In the study, a total of 60 participants were included, 30 of whom were systemically and
 periodontally healthy (control group) and 30 of whom were systemically healthy and had
 periodontitis (periodontitis group). GCF and serum samples were collected from the
 participants for biochemical analysis. ELISA method was used to determine IL-20, TNF-ฮฑ,
 IL1ฮฒ/IL-10, RANKL/OPG and MMP8 levels
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06091800
Non-Device Trial