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Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA) - Trial NCT06066424

Access comprehensive clinical trial information for NCT06066424 through Pure Global AI's free database. This Phase 1 trial is sponsored by M.D. Anderson Cancer Center and is currently Recruiting. The study focuses on Solid Tumors. Target enrollment is 54 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06066424
Phase 1
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06066424
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Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Study Focus

Solid Tumors

Rimiducid

Interventional

drug

Sponsor & Location

M.D. Anderson Cancer Center

Houston, United States of America

Timeline & Enrollment

Phase 1

Oct 24, 2023

Apr 30, 2040

54 participants

Primary Outcome

Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

Summary

To find the recommended dose of TROP2- CAR-NK cells that can be given to patients with
 advanced forms of solid tumors.

ICD-10 Classifications

Malignant neoplasm: Connective and soft tissue, unspecified
Malignant neoplasm of other connective and soft tissue
Carcinoma in situ, unspecified
Malignant neoplasms
Malignant neoplasm: Parametrium

Data Source

ClinicalTrials.gov

NCT06066424

Non-Device Trial