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Pharmacogenomics IND EXEMPT SNP Clinical Study - Crizotinib and Single Nucleotide Polymorphisms - Trial NCT06062810

Access comprehensive clinical trial information for NCT06062810 through Pure Global AI's free database. This Phase 2/3 trial is sponsored by Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair and is currently Not yet recruiting. The study focuses on Non-Small Cell Lung Cancer. Target enrollment is 600 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06062810
Phase 2/3
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06062810
View on ClinicalTrials.gov
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Pharmacogenomics IND EXEMPT SNP Clinical Study - Crizotinib and Single Nucleotide Polymorphisms
Explore the Relationship Between Single Nucleotide Polymorphisms and Crizotinib Response and Toxicity in Patients With Non-Small Cell Lung Cancer

Study Focus

Crizotinib - Usual

Interventional

drug

Sponsor & Location

Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair

Medicine Invention Design, Inc

Rockville, United States of America

Timeline & Enrollment

Phase 2/3

Oct 28, 2023

Dec 28, 2024

600 participants

Primary Outcome

Measure and Report Crizotinib oncology drug target ALK SNP Genotypes which are effectiveness-associated.,Measure and Report Crizotinib oncology drug target CYP4503A SNP Genotypes which are risk associated.

Summary

Explore the relationship between drug target ALK gene single nucleotide polymorphisms and
 XALKORI - Crizotinib therapeutic-effects in patients with non-small cell lung cancer, based
 on Oxford precisely sequencing drug targets' genes.
 
 Explore the relationship between drug target CYP4503A gene single nucleotide polymorphisms
 and XALKORI - Crizotinib side-effects in patients with non-small cell lung cancer, based on
 Oxford precisely sequencing drug targets' genes.

ICD-10 Classifications

Secondary malignant neoplasm of lung
Malignant neoplasm: Lower lobe, bronchus or lung
Malignant neoplasm: Middle lobe, bronchus or lung
Malignant neoplasm: Bronchus or lung, unspecified
Malignant neoplasm of bronchus and lung

Data Source

ClinicalTrials.gov

NCT06062810

Non-Device Trial