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Multimodal Recurrence Scoring System for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment - Trial NCT06032728

Access comprehensive clinical trial information for NCT06032728 through Pure Global AI's free database. This phase not specified trial is sponsored by First Affiliated Hospital, Sun Yat-Sen University and is currently Not yet recruiting. The study focuses on Renal Cell Carcinoma. Target enrollment is 488 participants.

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NCT06032728
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Trial Details
ClinicalTrials.gov โ€ข NCT06032728
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Multimodal Recurrence Scoring System for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment
A Multi-site, Open, Perspective Study of Prognostic Value and Benefit From Adjuvant Targeted Therapy of Stage III Clear Cell Renal Cell Carcinoma Based on Multimodal Recurrence Scoring System

Study Focus

Renal Cell Carcinoma

Sunitinib

Interventional

drug

Sponsor & Location

First Affiliated Hospital, Sun Yat-Sen University

Timeline & Enrollment

N/A

Oct 01, 2023

Oct 01, 2033

488 participants

Primary Outcome

Disease free survival

Summary

Whether patients with stage III clear cell renal cell carcinoma (ccRCC) should receive
 adjuvant targeted therapy or not is still on debate. The investigators invented a multimodal
 recurrence scoring system that was successfully categorise patients with stage III clear cell
 renal cell carcinoma into high-risk and low-risk groups with Hazard Ratio (HR) of 6.21. Here
 the investigators randomly assign assay-defined high risk patients of locally advanced ccRCC
 into adjuvant targeted therapy group and observation group. Disease free survival and overall
 survival are the end points of observation.

ICD-10 Classifications

Malignant neoplasm of kidney, except renal pelvis
Malignant neoplasm of renal pelvis
Secondary malignant neoplasm of kidney and renal pelvis
Benign neoplasm: Kidney
Benign neoplasm: Renal pelvis

Data Source

ClinicalTrials.gov

NCT06032728

Non-Device Trial