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GNT Induction Treatment in Locally Advanced NPC - Trial NCT06026878

Access comprehensive clinical trial information for NCT06026878 through Pure Global AI's free database. This Phase 3 trial is sponsored by Air Force Military Medical University, China and is currently Recruiting. The study focuses on Nasopharyngeal Carcinoma. Target enrollment is 228 participants.

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NCT06026878
Phase 3
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06026878
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GNT Induction Treatment in Locally Advanced NPC
Gemcitabine Combined With Nimotuzumab and Toripalimab as Induction Treatment Followed by Chemoradiotherapy for Locally Advanced Nasopharyngeal carcinoma-a Multicenter, Randomized Controlled Study

Study Focus

Nasopharyngeal Carcinoma

gemcitabine,nimotuzumab, toripalimab

Interventional

drug

Sponsor & Location

Air Force Military Medical University, China

Xi'an, China

Timeline & Enrollment

Phase 3

Sep 01, 2023

Sep 30, 2027

228 participants

Primary Outcome

overall response rate

Summary

The goal of this clinical trial is to compare overall response rate between gemcitabine,
 nimotuzumab and toripalimab as induction treatment and gemcitabine combined with cisplatine
 in paitents with locally advanced nasopharyngeal carcinoma. It aims to answer whether
 gemcitabine, nimotuzumab and toripalimab as induction treatment show non-inferiority compared
 to GP induction chemotherapy. Participants will be randomly divided into two induction
 treatment groups.

ICD-10 Classifications

Malignant neoplasm of nasopharynx
Malignant neoplasm: Nasopharynx, unspecified
Malignant neoplasm: Overlapping lesion of nasopharynx
Benign neoplasm: Nasopharynx
Malignant neoplasm: Posterior wall of nasopharynx

Data Source

ClinicalTrials.gov

NCT06026878

Non-Device Trial