Pure Global

A Study of XmAb®662 as Monotherapy or in Combination With Pembrolizumab in Advanced Solid Tumors - Trial NCT05996445

Access comprehensive clinical trial information for NCT05996445 through Pure Global AI's free database. This Phase 1 trial is sponsored by Xencor, Inc. and is currently Recruiting. The study focuses on Solid Tumors. Target enrollment is 210 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

Free Database
Powered by Pure Global AI
840K+ Trials
NCT05996445
Phase 1
Recruiting
biological
Trial Details
ClinicalTrials.govNCT05996445
View on ClinicalTrials.gov
Pure Global
DJ Fang

DJ Fang

MedTech Regulatory Expert

Need help with 30+ markets registration?

Pricing
A Study of XmAb®662 as Monotherapy or in Combination With Pembrolizumab in Advanced Solid Tumors
A Phase 1, First-in-Human, Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Activity of XmAb®662 in Monotherapy or in Combination With Pembrolizumab in Advanced Solid Tumors

Study Focus

Solid Tumors

XmAb662

Interventional

biological

Sponsor & Location

Xencor, Inc.

Charlottesville, United States of America

Timeline & Enrollment

Phase 1

Jul 28, 2023

Sep 30, 2030

210 participants

Primary Outcome

Incidence of dose-limiting toxicities (DLTs),Incidence and severity of treatment emergent adverse events (TEAEs)

Summary

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of
 intravenous administration of XmAb662 monotherapy or in combination with pembrolizumab in
 subjects with advanced solid tumors and to identify the recommended dose regimen that is safe
 and biologically effective for XmAb662.

ICD-10 Classifications

Malignant neoplasm: Connective and soft tissue, unspecified
Malignant neoplasm of other connective and soft tissue
Carcinoma in situ, unspecified
Malignant neoplasms
Malignant neoplasm: Parametrium

Data Source

ClinicalTrials.gov

NCT05996445

Non-Device Trial