Improving the Early Detection of Cardiometabolic Disease Risk - Trial NCT05885672

Timeline & Enrollment

Primary Outcome

Blood Pressure,Waist Circumference,Fasting blood glucose,Blood lipids,Metabolic syndrome severity score,Insulin,Homeostatic Model Assessment for Insulin Resistance (HOMA-IR),Tumor necrosis factor-alpha,Body fat percentage,Fat mass,Fat-free mass,Body circumferences,Heart Rate Variability,Cardiac Baroreflex Sensitivity,Flow-mediated changes in vascular diameter,Flow-mediated changes in blood flow,Flow-mediated changes in blood pressure,Flow-mediated changes in vascular conductance,Flow-mediated changes in vascular resistance,Flow-mediated changes in skeletal muscle oxygenation,Passive Limb Movement Mediated Changes in Vascular Diameter,Passive Limb Movement Mediated Changes in Blood Flow,Passive Limb Movement Mediated Changes in Blood Pressure,Passive Limb Movement Mediated Changes in Vascular Conductance,Passive Limb Movement Mediated Changes in Vascular Resistance,Passive Limb Movement Mediated Changes in Skeletal Muscle Oxygenation,Carotid-Femoral Pulse Wave Velocity,Cold Pressor Test Blood Pressure Responses,Cold Pressor Test Heart Rate Responses,Cold Pressor Test Vascular Conductance Responses,Cold Pressor Test Vascular Resistance Responses,Cold Pressor Test stroke volume Responses,Cold Pressor Test Cardiac Output Responses,Metaboreflex Blood Pressure Responses,Metaboreflex Heart Rate Responses,Metaboreflex Vascular Conductance Responses,Metaboreflex Vascular Resistance Responses,Metaboreflex Stroke Volume Responses,Metaboreflex Cardiac Output Responses,Functional Sympatholysis Blood Flow Responses,Functional Sympatholysis Vascular Conductance Responses,Functional Sympatholysis Vascular Resistance Responses,Functional Sympatholysis Blood Pressure Responses,Gait velocity,Gait velocity,Stride Length,Stride Length,Stride Width,Stride Width,Gait Cadence,Gait Cadence,Ankle joint angle,Ankle joint moment,Ankle joint angle,Ankle joint moment,Knee joint angle,Knee joint moment,Knee joint angle,Knee joint moment,Hip joint angle,Hip joint moment,Hip joint angle,Hip joint moment,Ground reaction forces,Ground reaction forces,Center of pressure - right leg,Center of pressure - left leg,Center of pressure - bilateral,Timed-up and go,Sit-to-stand,Time Up and Down Stairs,Isometric strength,Visceral adipose tissue,Subcutaneous adipose tissue,Motivation and Attitudes Towards Health,Readiness for Behavior Change,Treatment Seeking Behavior

Summary

The goal of this observational study is to reduce an individual's cardiometabolic disease
 risk by improving the ability to detect cardiometabolic disease risk in young adults through
 the use of novel technologies that increase access to and examine the utility of, a
 continuous metabolic syndrome severity score. An additional goal of this study is to
 understand the barriers to engagement in health-promoting behaviors and beliefs about
 interventions aimed at mitigating metabolic syndrome risk through a brief online lifestyle
 intervention.
 
 The main question[s] it aims to answer are:
 
 - Can a smartphone-based imaging system accurately predict a continuous metabolic syndrome
 severity score, in addition to other markers of cardiometabolic disease, in young
 adults?
 
 - What is the relationship between autonomic dysfunction and metabolic syndrome severity
 in a cohort of young adults?
 
 - What is the relationship between peripheral vascular dysfunction and metabolic syndrome
 severity in a cohort of young adults?
 
 - What are the associations between metabolic syndrome severity and gait and functional
 ability in young adults using novel markerless motion capture technology?
 
 - What are the attitudes and barriers towards lifestyle interventions targeted to reduce
 metabolic syndrome severity?
 
 - What are the treatment-seeking and willingness to engage behaviors toward a webpage
 focused on lifestyle interventions to reduce metabolic syndrome severity?
 
 Participants will be asked to undergo several assessments across four separate days which are
 design designed to determine the associations between cardiometabolic health markers and
 components of:
 
 - body composition
 
 - cardiovascular function
 
 - functional ability
 
 - attitudes and behaviors towards health-related interventions

ICD-10 Classifications