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Effect of Renin Angiotensin Aldosterone System Genetic Polymorphism on the Pharmacological Effect of Mineralocorticoid Receptor Antagonists in Patients With Myocardial Infarction - Trial NCT05873400

Access comprehensive clinical trial information for NCT05873400 through Pure Global AI's free database. This phase not specified trial is sponsored by Ain Shams University and is currently Recruiting. The study focuses on Myocardial Infarction. Target enrollment is 102 participants.

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NCT05873400
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Trial Details
ClinicalTrials.gov โ€ข NCT05873400
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Effect of Renin Angiotensin Aldosterone System Genetic Polymorphism on the Pharmacological Effect of Mineralocorticoid Receptor Antagonists in Patients With Myocardial Infarction

Study Focus

Myocardial Infarction

Observational

Sponsor & Location

Ain Shams University

Cairo, Egypt

Timeline & Enrollment

N/A

Aug 01, 2022

Apr 01, 2024

102 participants

Primary Outcome

Genetic polymorphism

Summary

Early treatment of Myocardial Infarction patients with mineralocorticoid receptor antagonist
 with help reduces the incidence of cardiac remodeling and development into heart failure.
 Also studying aldosterone synthase (CYP11B2) and mineralocorticoid receptor (NR3C2) gene
 polymorphisms in Egyptian Myocardial Infarction patients will help tailor medication therapy
 and optimize therapeutic effects with the least adverse effects.

ICD-10 Classifications

Acute myocardial infarction
Acute myocardial infarction, unspecified
Old myocardial infarction
Subsequent myocardial infarction
Observation for suspected myocardial infarction

Data Source

ClinicalTrials.gov

NCT05873400

Non-Device Trial