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Study of HBV Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis B - Trial NCT05770895

Access comprehensive clinical trial information for NCT05770895 through Pure Global AI's free database. This Phase 1 trial is sponsored by Gilead Sciences and is currently Recruiting. The study focuses on Chronic Hepatitis B. Target enrollment is 70 participants.

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NCT05770895
Phase 1
Recruiting
biological
Trial Details
ClinicalTrials.gov โ€ข NCT05770895
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Study of HBV Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis B
A Phase 1a/1b Study to Evaluate the Safety and Tolerability of Repeated Doses of Nonreplicating Arenavirus Vector Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis B (CHB)

Study Focus

Chronic Hepatitis B

GS-2829

Interventional

biological

Sponsor & Location

Gilead Sciences

Auckland, New Zealand

Timeline & Enrollment

Phase 1

Apr 03, 2023

Nov 01, 2024

70 participants

Primary Outcome

Percentage of Participants With Treatment-emergent Adverse Events (AEs) and Serious Adverse Events (SAEs),Percentage of Participants With Treatment-emergent Laboratory Abnormalities

Summary

The goal of this clinical study is to learn more about GS-2829 and GS-6779 in healthy
 participants and participants with CHB.

ICD-10 Classifications

Acute hepatitis B
Chronic viral hepatitis B without delta-agent
Acute delta-(super)infection in chronic hepatitis B
Chronic viral hepatitis B without delta-agent : other and unspecified phase
Chronic viral hepatitis B without delta-agent : immune-tolerant phase

Data Source

ClinicalTrials.gov

NCT05770895

Non-Device Trial