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The Influence of Endurance Sports Activity on the Oral Microbiota of Young Adults. - Trial NCT05765422

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NCT05765422
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Trial Details
ClinicalTrials.gov โ€ข NCT05765422
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The Influence of Endurance Sports Activity on the Oral Microbiota of Young Adults.
Sport and Health a Pilot Study: Impact of Endurance Physical Activity on the Microbiological Homeostasis of the Oral Cavity of Young Adults

Study Focus

Microbial Colonization

salivar and gum sampling

Interventional

other

Sponsor & Location

Centre Hospitalier Universitaire de Nice

Nice, France

Timeline & Enrollment

N/A

Mar 15, 2023

Mar 15, 2026

200 participants

Primary Outcome

Analysis of the oral microbiota in healthy individuals engaged in endurance physical activity at different levels.

Summary

The oral cavity is an easily accessible anatomical site that accurately reflects the health
 of the individual. The mouth is considered an early indicator of biological aging, leading to
 the identification of oral biomarkers predictive of future alterations. Current data show
 that the oral health of high level athletes is globally altered with an increase in
 cariogenic indexes, an increased incidence of periodontitis, dental trauma and dry mouth
 syndromes. Few studies have focused on the oral microbiota compared to mouthguards used in
 rugby or boxing which seem to induce dysbiosis, a recent study shows an effect of ketogenic
 diet on bacterial changes in the mouth of endurance athletes. This project focuses on the
 impact of intensive sport practice on oral health and the identification of oral biomarkers
 associated with physical activity. The objective of this study is to investigate the impact
 of the amount of endurance sport practice on oral microbiota and oral health in young adults.
 the hypothesis is that a sedentary lifestyle and high-level sport induce depletion and/or
 changes in the oral microbiota compared to regular physical activity.

ICD-10 Classifications

Bacterial infection of unspecified site
Other bacterial infections of unspecified site
Bacterial, viral and other infectious agents
Cholera
Other specified bacterial intestinal infections

Data Source

ClinicalTrials.gov

NCT05765422

Non-Device Trial