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Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations. - Trial NCT05742802

Access comprehensive clinical trial information for NCT05742802 through Pure Global AI's free database. This Phase 3 trial is sponsored by AstraZeneca and is currently Recruiting. The study focuses on Chronic Obstructive Pulmonary Disease (COPD). Target enrollment is 2544 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT05742802
Phase 3
Recruiting
combination product
Trial Details
ClinicalTrials.gov โ€ข NCT05742802
View on ClinicalTrials.gov
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Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations.
A Phase III, Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Extension Study to Evaluate the Long-term Efficacy and Safety of Tozorakimab (MEDI3506) in Participants With Chronic Obstructive Pulmonary Disease (COPD) With a History of Exacerbations.

Study Focus

Tozorakimab

Interventional

combination product

Sponsor & Location

AstraZeneca

Sheffield,Lincoln,Newport Beach,Boynton Beach,Ormond Beach,Pensacola,Tampa,Evergreen Park,Normal,Kansas City,Bowling Green,Baton Rouge,Zachary,Missoula,Gastonia,Tulsa,Rock Hill,Houston,Caba,Melbourne,, Argentina,Australia,Belgium,Brazil,Bulgaria,Canada,Colombia,Czech,Denmark,Finland,Germany,Greece,Hun

Timeline & Enrollment

Phase 3

Mar 06, 2023

Aug 27, 2026

2544 participants

Primary Outcome

Time to first severe COPD exacerbation in former smokers.

Summary

Subjects who completed either OBERON or TITANIA will be offered the opportunity to consent
 for this Multicentre, Double-blind, Randomised, Placebo controlled, Parallel Group, Phase 3,
 extension study to evaluate the safety and efficacy of Tozorakimab in adult participants with
 symptomatic COPD.

ICD-10 Classifications

Other chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease, unspecified
Other specified chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
Chronic obstructive pulmonary disease with acute lower respiratory infection

Data Source

ClinicalTrials.gov

NCT05742802

Non-Device Trial