Study on Initiation and Immunological Mechanism of Childbirth - Trial NCT05604768
Access comprehensive clinical trial information for NCT05604768 through Pure Global AI's free database. This phase not specified trial is sponsored by Beijing Ditan Hospital and is currently Recruiting. The study focuses on Pregnancy. Target enrollment is 40 participants.
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Study Focus
Observational
Sponsor & Location
Beijing Ditan Hospital
Timeline & Enrollment
N/A
Mar 28, 2022
Mar 28, 2025
Primary Outcome
The change of the frequency of myeloid-derived suppressor cells (MDSCs) in normal pregnancy and delivery,The change of functional molecules expression of myeloid-derived suppressor cells (MDSCs) in normal pregnancy and delivery,The change of the frequency of plasmacytoid dendritic cells (pDC) in normal pregnancy and delivery,The change of the functional molecules expression of plasmacytoid dendritic cells (pDC) in normal pregnancy and delivery,The change of the frequency of Nature Killer (NK) cells in normal pregnancy and delivery,The change of the functional molecules expression of Nature Killer (NK) cells in normal pregnancy and delivery,The change of the content of cffDNA in normal pregnancy and delivery
Summary
This study is a prospective observational study. The participants including 40 pregnant women
 who have been filed and delivered in our hospital will enrolled, collect venous blood will be
 collected at different stages of pregnancy, delivery, postpartum to detect the concentration
 of fetal free DNA, the frequency of associated immune cells, and the expression of functional
 molecules, so as to explore the immunological mechanism of delivery initiation.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT05604768
Non-Device Trial