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Prognostic Value of Right Ventricular Myocardial Strain in Patients With Acute Myocardial Infarction - Trial NCT05404555

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NCT05404555
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Trial Details
ClinicalTrials.gov โ€ข NCT05404555
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Prognostic Value of Right Ventricular Myocardial Strain in Patients With Acute Myocardial Infarction
Prognostic Value of Right Ventricular Myocardial Strain in Patients With Acute Myocardial Infarction With Different Infarction-related Vessels

Study Focus

two-dimensional speckle tracking echocardiography

Observational

other

Sponsor & Location

Peking University Third Hospital

Beijing, China

Timeline & Enrollment

N/A

Oct 01, 2021

Oct 30, 2024

200 participants

Primary Outcome

Major Adverse Cardiovascular Events

Summary

For a long time, the right ventricle has been the forgotten chamber, but with the deepening
 of people's understanding of the disease, right ventricular dysfunction has become an
 important factor to evaluate the disease progression and late prognosis of patients with AMI.
 Right ventricular myocardial strain derived from two-dimensional speckle tracking
 echocardiography is a new method for early evaluation of regional and global right
 ventricular systolic function, and its repeatability is much higher than that of LVEF. Acute
 inferior myocardial infarction is often caused by occlusion of the proximal middle segment of
 the right coronary artery. Many studies have confirmed that RVMS is an independent predictor
 of poor prognosis in patients with AIMI. However, 60% of the right ventricular systolic
 function is contributed by the left ventricle and interventricular septum, and the left
 anterior descending branch and the left circumflex branch are the main sources of blood
 supply to the left ventricle and interventricular septum, so in theory, non-RCA occlusion can
 also lead to varying degrees of right ventricular dysfunction. However, there are few studies
 on the role of RVMS in predicting the prognosis of AMI patients caused by non-RCA occlusion.
 Therefore, the purpose of this study is to prospectively study the value of dynamic changes
 of RVMS in predicting the prognosis of patients with acute myocardial infarction with
 different infarct-related vessels, in order to provide more clinical reference information
 for the diagnosis and treatment of AMI.

ICD-10 Classifications

Acute myocardial infarction
Acute myocardial infarction, unspecified
Acute subendocardial myocardial infarction
Certain current complications following acute myocardial infarction
Other current complications following acute myocardial infarction

Data Source

ClinicalTrials.gov

NCT05404555

Non-Device Trial