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Treatment of Hepatitis c by Using Direct-acting Antiviral - Trial NCT05372874

Access comprehensive clinical trial information for NCT05372874 through Pure Global AI's free database. This phase not specified trial is sponsored by Tanta University and is currently Not yet recruiting. The study focuses on Hepatitis C. Target enrollment is 50 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT05372874
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Trial Details
ClinicalTrials.gov โ€ข NCT05372874
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Treatment of Hepatitis c by Using Direct-acting Antiviral
Evaluation of the Effect of Direct-Acting Antiviral Agents on Melatonin Level in Chronic Hepatitis C Patients in Egypt.

Study Focus

Hepatitis C

Direct Acting Antivirals

Observational

drug

Sponsor & Location

Tanta University

Timeline & Enrollment

N/A

May 06, 2022

Jul 30, 2022

50 participants

Primary Outcome

Change in malondialdehyde (MDA) level.,Change in melatonin level.

Summary

Patients with hepatitis c showed increased level of oxidative stress. Increased level of
 serum lipid peroxidation leads to the production of toxic mediators as malondialdehyde (MDA)
 which lead to disease progression. Chronic stress shunt tryptophan which is essential amino
 acid toward kynurenic pathway leading to lower level of serotonin and melatonin level.
 Currently, direct-acting antivirals (DAAs) show well-established efficacy against hepatitis C
 virus (HCV).

ICD-10 Classifications

Acute hepatitis C
Chronic viral hepatitis C
Viral hepatitis
Chronic viral hepatitis
Unspecified viral hepatitis

Data Source

ClinicalTrials.gov

NCT05372874

Non-Device Trial