Pathogen Detection in HIV-infected Children With Non-malarial Febrile Illnesses Using Metagenomic Sequencing - Trial NCT05085158
Access comprehensive clinical trial information for NCT05085158 through Pure Global AI's free database. This phase not specified trial is sponsored by Makerere University and is currently Not yet recruiting. The study focuses on HIV Infection. Target enrollment is 200 participants.
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Study Focus
Observational
Sponsor & Location
Makerere University
Timeline & Enrollment
N/A
Jun 01, 2022
Oct 01, 2024
Primary Outcome
Prevalence of microbial pathogens in NMFIs HIV-infected children and adolescents
Summary
In Uganda, 130,000 children (0-14 years of age) were living with HIV in 2018. Last year,
 nearly 450 infants acquired HIV every day; most of them during childbirth and these are at
 extremely high risk of dying in the first two years of life from treatable infections which
 present with fever. While fevers are commonly attributed to malaria, most fevers in African
 children are not due to malaria and clinicians are challenged by the similar clinical
 features of wide spectrum of potential aetiologies. The prevalence of treatable causes of
 non-malarial febrile illnesses in children in Africa has been reported to be 45%.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT05085158
Non-Device Trial