Early Diagnosis of Leukemic Children Patients Based on Clinical, Age Estimation and Radiographical Evaluation of Oral Affection - Trial NCT04756258

Timeline & Enrollment

Primary Outcome

Ability to diagnose leukemic child patients who don't have manifesting systemic clinical signs from their clinical and radiographical oral signs

Summary

Early diagnosis of leukemia which is malignant tumor affecting bone especially in children is
 import to allow early intervention improving prognosis. It is known that leukemic patients
 suffer from clinical signs as anemia, thrombocytopenia, and pronounced hepatosplenomegaly or
 lymphadenopathy. However, sometimes these clinical signs may be not clearly manifested and
 may look like anemia. The early diagnosis could be achieved through dentist by accessing
 clinical and radiographical signs such as oral masses, gingival bleeding /or enlargement and
 oral ulceration with radiographical features including focal or generalized osteolysis of
 bone with presence of moth eating appearance and even with abnormal teeth chronology
 regarding teeth morphology, germ formation of permanent teeth and their sequence of eruption.
 Therefore, accessing of these special clinical and radiographical features by the dentist
 could help in early diagnosis of leukemic children patients

ICD-10 Classifications