Improving Implementation of Evidence-based Approaches and Surveillance to Prevent Bacterial Transmission and Infection - Trial NCT04600973
Access comprehensive clinical trial information for NCT04600973 through Pure Global AI's free database. This phase not specified trial is sponsored by Trustees of Dartmouth College and is currently Not yet recruiting. The study focuses on Infection. Target enrollment is 6000 participants.
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Study Focus
Sponsor & Location
Trustees of Dartmouth College
Timeline & Enrollment
N/A
Jul 01, 2021
Jun 30, 2026
Primary Outcome
ESKAPE Transmission Events
Summary
Surgical site infections (SSIs) are associated with increased patient morbidity, mortality,
 and healthcare costs. ESKAPE (Enterococcus, S. aureus, Klebsiella, Acinetobacter,
 Pseudomonas, and Enterobacter spp.) pathogens are particularly pathogenic because they have
 increased capacity to acquire resistance and virulence traits. The investigators have proven
 that a multifaceted program involving improved basic perioperative preventive measures can
 generate substantial reductions in S. aureus transmission and significant reductions in SSIs
 (88% reduction as compared to usual care). In this study, the investigators aim to examine
 the relative effectiveness of each component of this program in controlling ESKAPE
 transmission and reducing SSIs and to identify an optimal implementation strategy for
 national dissemination. Randomization occurs at the site level, and sites adopt preventative
 programs. This work will improve perioperative patient safety for the 51 million patients who
 undergo surgery each year.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT04600973
Non-Device Trial