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Deep Learning Magnetic Resonance Imaging Radiomic Predict Platinum-sensitive in Patients With Epithelial Ovarian Cancer - Trial NCT04511481

Access comprehensive clinical trial information for NCT04511481 through Pure Global AI's free database. This phase not specified trial is sponsored by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University and is currently Recruiting. The study focuses on Predictive Cancer Model. Target enrollment is 93 participants.

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NCT04511481
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Trial Details
ClinicalTrials.gov โ€ข NCT04511481
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DJ Fang

DJ Fang

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Deep Learning Magnetic Resonance Imaging Radiomic Predict Platinum-sensitive in Patients With Epithelial Ovarian Cancer

Study Focus

Predictive Cancer Model

Radiomic Algorithm

Observational

other

Sponsor & Location

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Guangzhou, China

Timeline & Enrollment

N/A

Apr 15, 2020

Jan 01, 2021

93 participants

Primary Outcome

Platinum sensitivity

Summary

Platinum-sensitive is an important basis for the treatment of recurrent epithelial ovarian
 cancer (EOC) without effective methods to predict.We aimed to develop and validate the EOC
 deep learning system to predict the platinum-sensitive of EOC patients through analysis of
 enhanced magnetic resonance imaging (MRI) images before initial treatment.Ninety-three EOC
 patients received platinum-based chemotherapy (= 4 cycles) and debulking surgery from Sun
 Yat-sen Memorial Hospitalin China from January 2011 to January 2020 were enrolled. This
 deep-learning EOC signature achieved a high predictive power for platinum-sensitive, and the
 signature based on MRI whole volume is better than that on primary tumor area only.

ICD-10 Classifications

Personal history of chemotherapy for neoplastic disease
Malignant neoplasm, primary site unspecified
Malignant neoplasm, without specification of site
Malignant neoplasm, primary site unknown, so stated

Data Source

ClinicalTrials.gov

NCT04511481

Non-Device Trial