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Measuring Biomarker Response to AMP-514 in Blood Samples From Patients With Solid Tumors Undergoing Radiotherapy - Trial NCT02153151

Access comprehensive clinical trial information for NCT02153151 through Pure Global AI's free database. This phase not specified trial is sponsored by Sidney Kimmel Cancer Center at Thomas Jefferson University and is currently Completed. The study focuses on Unspecified Adult Solid Tumor, Protocol Specific. Target enrollment is 21 participants.

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NCT02153151
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Trial Details
ClinicalTrials.gov โ€ข NCT02153151
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Measuring Biomarker Response to AMP-514 in Blood Samples From Patients With Solid Tumors Undergoing Radiotherapy
A Pilot Study to Evaluate the In-vitro Effect of AMP-514, a PD-1 Inhibitor, on Peripheral Blood T Cell Proliferation and Cytokine Production From Patients With Solid Malignancies Treated With Radiotherapy (RT)

Study Focus

Cytology specimen

Observational

other

Sponsor & Location

Sidney Kimmel Cancer Center at Thomas Jefferson University

Thomas Jefferson University

Philadelphia, United States of America

Timeline & Enrollment

N/A

Nov 11, 2013

Jul 14, 2016

21 participants

Primary Outcome

Change in peripheral blood T cell proliferation (stimulation) and cytokine production in vitro

Summary

This pilot research trial studies the response in blood cells to AMP-514, a drug shown to
 increase immune response (capacity to fight against infections and cancer) against cancer in
 patients with solid tumors undergoing radiotherapy. Measuring changes in biomarkers may help
 doctors decide if AMP-514 should be combined with radiotherapy and when is the best time to
 combine the drug with radiation.

ICD-10 Classifications

Carcinoma in situ, unspecified
Malignant neoplasm, without specification of site
Malignant neoplasm, primary site unspecified
Carcinoma in situ of other and unspecified genital organs
Malignant neoplasm: Connective and soft tissue, unspecified

Data Source

ClinicalTrials.gov

NCT02153151

Non-Device Trial