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Capecitabine and Celecoxib in Patients With Solid Cancers That Have Been Previously Treated With Standard Therapies - Trial NCT01705106

Access comprehensive clinical trial information for NCT01705106 through Pure Global AI's free database. This Phase 1 trial is sponsored by University of Chicago and is currently Terminated. The study focuses on Unspecified Adult Solid Tumor, Protocol Specific. Target enrollment is 21 participants.

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NCT01705106
Phase 1
Terminated
drug
Trial Details
ClinicalTrials.gov โ€ข NCT01705106
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Capecitabine and Celecoxib in Patients With Solid Cancers That Have Been Previously Treated With Standard Therapies
A Drug-drug Interaction Study of Capecitabine and Celecoxib in Patients With Advanced Solid Malignancies

Study Focus

capecitabine

Interventional

drug

Sponsor & Location

University of Chicago

Chicago, United States of America

Timeline & Enrollment

Phase 1

Aug 29, 2012

Feb 10, 2016

21 participants

Primary Outcome

AUC of Celecoxib on Combination Therapy (Day 14) and AUC of Celecoxib on Celecoxib Monotherapy(Day 7)

Summary

This clinical trial studies capecitabine and celecoxib in treating patients with solid
 malignancies that are metastatic or cannot be removed by surgery. Drugs used in chemotherapy,
 such as capecitabine, work in different ways to stop the growth of tumor cells, either by
 killing the cells or by stopping them from dividing. Celecoxib may stop the growth of tumor
 cells by blocking some of the enzymes needed for cell growth. Giving capecitabine and
 celecoxib together may be an effective treatment for solid malignancies.

ICD-10 Classifications

Carcinoma in situ, unspecified
Malignant neoplasm, without specification of site
Malignant neoplasm, primary site unspecified
Carcinoma in situ of other and unspecified genital organs
Malignant neoplasm: Connective and soft tissue, unspecified

Data Source

ClinicalTrials.gov

NCT01705106

Non-Device Trial