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PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors - Trial NCT01158300

Access comprehensive clinical trial information for NCT01158300 through Pure Global AI's free database. This Phase 1 trial is sponsored by Pediatric Brain Tumor Consortium and is currently Completed. The study focuses on Brain and Central Nervous System Tumors. Target enrollment is 28 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT01158300
Phase 1
Completed
drug
Trial Details
ClinicalTrials.gov โ€ข NCT01158300
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PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors
Phase I and Pharmacokinetic Trial of PTC299 in Pediatric Patients With Refractory or Recurrent CNS Tumors

Study Focus

VEGF inhibitor PTC299

Interventional

drug

Sponsor & Location

Pediatric Brain Tumor Consortium

San Francisco,Washington,Chicago,Durham,Philadelphia,Pittsburgh,Memphis,Houston, United States of America

Timeline & Enrollment

Phase 1

Nov 01, 2010

Jan 01, 2015

28 participants

Primary Outcome

Maximum-tolerated dose,Adverse events

Summary

RATIONALE: PTC299 may stop the growth of tumor cells by blocking blood flow to the tumor.
 
 PURPOSE: This phase I trial is studying the side effects and the best dose of PTC299 in
 treating young patients with recurrent or refractory primary central nervous system tumors.

ICD-10 Classifications

Malignant neoplasm: Overlapping lesion of brain and other parts of central nervous system
Malignant neoplasm: Central nervous system, unspecified
Benign neoplasm of brain and other parts of central nervous system
Malignant neoplasm of brain
Secondary malignant neoplasm of other and unspecified parts of nervous system

Data Source

ClinicalTrials.gov

NCT01158300

Non-Device Trial