Calibrating Imaging Techniques to Study Blood Flow - Trial NCT00546091

Timeline & Enrollment

Summary

This study will explore the uses of three noninvasive imaging techniques-thermography, laser
 Doppler imaging, and multispectral imaging-to test the blood flow of healthy volunteers. By
 comparing these three techniques, researchers will be able to train these imaging systems to
 better evaluate skin types and blood flow. The study will also test computer programs that
 have been developed to correct for the effects of curvature and body hair on the images.
 
 Healthy volunteers must be older than 18 years of age and may not have had a history of
 malignant tumors, skin disease, or vascular disease.
 
 Participants will undergo the following procedures on an outpatient basis:
 
 Three different types of images taken of the participant s forearm
 
 - Thermography infrared thermal imaging to map skin temperature
 
 - Laser Doppler imaging low-powered laser imaging to map blood flow in the skin
 
 - Multispectral imaging near-infrared light imaging to measure total blood flow and oxygen
 levels in the skin
 
 A reactive hyperemia experiment, in which multispectral images will be taken of the
 participant s forearm during and after the use of a blood pressure cuff
 
 A hair removal experiment, in which images will be collected of the participant s forearm in
 separate scans done before and after the hair is removed with a topical hair removal solution
 
 The entire series of exams will take approximately one hour to perform.

ICD-10 Classifications