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The Effect of Different New Zealand Foods and Beverages on Energy Expenditure, Blood Sugar and Appetite After Eating - Trial ANZCTR12622000027718

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ANZCTR12622000027718
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Trial Details
Australian New Zealand Clinical Trials Registry โ€ข ANZCTR12622000027718
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The Effect of Different New Zealand Foods and Beverages on Energy Expenditure, Blood Sugar and Appetite After Eating
SYNERGY Acute Single-Product Sub-Study: The Utility of Individual NZ Origin Food and Beverage Products for the Acute Enhancement of Postprandial Thermogenesis, Glycaemia and Appetite in Healthy or Prediabetic Adults

Study Focus

Prediabetes

Interventional

other

Sponsor & Location

The University of Auckland

New Zealand Ministry of Business, Innovation and Employment (MBIE), National Science Challenge: High Value Nutrition Programme

New Zealand

Timeline & Enrollment

Not Applicable

Jan 17, 2022

Jun 30, 2023

Primary Outcome

Composite change in both fasted and postprandial resting energy expenditure (following consumption of product) assessed using indirect calorimetry;; Composite change in respiratory quotient (substrate utilisation) ;; Change in venous blood glucose (collected from antecubital vein via cannula inserted at start of day)

Summary

It is well known that what we eat affects our health. It is now also well recognised that some products contain additional โ€˜bioactiveโ€™ properties, such as high protein content, that can provide health benefit above a foodโ€™s nutritional value. Firstly, it has been suggested that such โ€˜functionalโ€™ foods could increase the amount of energy (calories) burned in the hours after eating. Secondly, these products may be able to promote a preferential breakdown of fat after the ingestion of meals. Thirdly, foods and beverages of a bioactive nutrient composition may help to regulate blood sugar response. Finally, it is documented that the consumption of certain products could maximise feelings of fullness for longer. It is hypothesised that food and beverage products containing a greater content of polyphenols, complex carbohydrates and/or protein may enhance energy expenditure, blood sugar and appetite after eating. This study will be composed of four individual trials in which different food or beverage products will be tested for their efficacy in enhancing these markers of metabolic health. Moreover, research has recently suggested that energy expenditure after eating may be decreased among individuals with prediabetes, however these linkages with abnormal blood sugar control remain largely unexplored. It is also not understood whether energy expenditure after eating can be increased among prediabetic individuals through nutritional intervention. Finally, this study will investigate any differences in energy expenditure after eating between Caucasian European and Asian Chinese individuals.

ICD-10 Classifications

Diabetes mellitus
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, unspecified
Other specified diabetes mellitus
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent

Data Source

Australian New Zealand Clinical Trials Registry

ANZCTR12622000027718

Non-Device Trial